Senior Manager, Accounting

Location: South San Francisco
Posted on: June 23, 2025

Job Description:

The Position Are you someone who thrives in a fast-paced environment, enjoys diving into financial data, building financial processes and operations, developing and implementing financial controls, and is passionate about turning insights into action? We’re looking for a skilled and detail-oriented Senior Manager, Accounting . In this role, you will be reporting directly to the Director of Accounting, Assistant Controller. You’ll be responsible for managing operational accounting, including, but not limited to, driving financial statement closes, general ledger transactions and financial statement audits and review. In addition, you will be responsible for the development, preparation and oversight of the company’s research and development (R&D) accounting and accrual processes, including the company’s clinical trial accounting for multiple ongoing studies. You’ll also serve as a strategic partner to the Director of Accounting, helping to shape and implement scalable financial processes and policies that support long-term growth and internal control over financial reporting. You will play a key part expanding and developing the Finance and Accounting team as the organization continues to grow. The Impact You’ll Have Manage the monthly, quarterly and annual financial close preparation and review of journal entries, account reconciliations and key financial reports and presentations. Oversee R&D accounting and compliance with GAAP, working closely with R&D project managers and teams. This includes developing and maintaining strong internal controls particularly around clinical trial accounting and accruals. Serve as a key point contact for the company’s external audit firm. Coordinate audit deliverables (PBCs) and ensure timely, accurate responses to audit requests. Partner with cross-functional teams and external service providers (e.g. CROs) to implement scalable financial processes, policies, and systems that support company growth and financial processes. Facilitate effective communication across departments to ensure alignment and smoother implementation of financial processes. Identify opportunities for process improvements and implement best practices to further enhance efficiency and accuracy in financial operations. Participate in special projects, such as financial system implementations and enhancements, and perform other related duties as assigned. What We’re Looking For Bachelor’s degree in accounting, finance, or related field. CPA certification and/or public accounting experience preferred. 8 years of relevant work experience, including 2-3 years in a leadership or supervisory role. Biotech industry and public company experience preferred. Strong understanding of US GAAP, financial reporting and SOX compliance regulations. Effective communicator with good verbal and written communication skills. Excellent project management skills and the ability to collaborate with cross-functional leaders and others, both inside and outside the company. Attention to detail and ability to work independently and lead processes. Ability to work in a hybrid working environment with on-site attendance 2-3 days a week. Advanced MS Office skills (Word, Excel, PowerPoint). Accounting ERP system experience, preferably NetSuite. Familiarity with procure-to-pay systems (e.g. Coupa) and financial close software (e.g. FloQast). Strong ethical values with a focus on authenticity, accountability, excellence and integrity. A collaborative team member with a passion for bringing novel therapies to patients with unmet medical needs. About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. We are advancing a pipeline using our Compass platform, which allows us to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process we refer to as variant functionalization. Our Compass platform has been purpose-built to inform all phases of our drug discovery and development process through clinical trial design. We are currently advancing two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease, or CKD. Our goal is to bring novel precision medicines to patients with common diseases, which is where we believe we can maximize our impact on human health. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. Our Core Values Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True – Our integrity is foundational; it guides us no matter the obstacle. The expected salary range for this role at a Senior Manager level for employees located in the San Francisco Bay Area is $162,000 – 199,000. Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of a candidate’s job level and starting salary will depend upon a variety of job-related factors, which may include professional experience, skills and job location. The expected salary range for this role may be modified in the future. Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.

Keywords: , Palo Alto , Senior Manager, Accounting, Accounting, Auditing , South San Francisco, California