Scientist, Organic Chemistry
Company: Kodiak Sciences
Location: Palo Alto
Posted on: November 22, 2022
Kodiak Sciences, Inc. is a fast-growing clinical-stage
biopharmaceutical company with a singular focus in ophthalmology.
The company is committed to progressing and expanding its pipeline
through research, development, and commercialization of
transformative therapeutics for prevention, treatment, and, when
possible, cure of high-prevalence ophthalmology diseases. Our
unique Antibody Biopolymer Conjugate (ABC) platform--- merges the
fields of protein engineering, polymer chemistry, small molecule
drug discovery, bioconjugation, and drug release, and is at the
core of our discovery engine.
Kodiak Sciences, Inc. is seeking a highly motivated Organic Chemist
to join a dynamic multidisciplinary team in our Discovery Medicine
group designing novel disruptive ophthalmic medicines and delivery
platforms. This is an outstanding opportunity for a well-rounded
chemistry generalist with a keen scientific aptitude and curiosity
coupled with passion for using organic chemistry to tackle the
broadest variety of synthetic challenges ranging from drug
discovery, linker design and chemistry, bioconjugation, polymer
synthesis, functionalization and characterization.
The successful candidate must combine strong theoretical knowledge
and comprehension of organic chemistry in the broadest sense,
mastery of standard and modern synthetic chemistry techniques,
practical bench-top skills, independence, and resourcefulness in
reaction design with tenacity in route selection and optimization.
Strong command of analytical methods and instrumentation, hands-on
experience with separation, isolation, and purification techniques,
and skills in summarizing and interpreting analytical and
functional data for determining identity and purity of small or
large molecules are a must.
The ideal candidate stands out through a "can-do attitude" coupled
with resourcefulness, independence of thought, problem-solving
skills, determination to make an impact, as well as ambition for
professional and personal growth. A strong natural sense of
accountability, research integrity, and documentation are a must.
We are searching for highly motivated, team-oriented scientists
with good technical skills and a track record of problem-solving to
join our team of dedicated professionals devoted to advancing novel
treatments to unmet medical indications.
- Synthesis of organic chemistry compounds in support of a
plurality of in-house R&D campaigns with an emphasis on
designing and reducing to practice workable synthetic routes
towards sophisticated custom building blocks, small molecules,
bio-tools, novel linkers, and drug-release technology.
- Design, synthesis, and scale-up of functional monomers.
- Independently design and conduct experiments within the project
and corporate goals. Analyze, interpret, organize, capture, and
document data and effectively communicate results in team
- Engagement in relationship management with CROs for
- Collaborate with scientific colleagues across functional
disciplines and departments.
- Ph.D. in preparative organic chemistry, medicinal chemistry, or
related discipline, preferably with 0-2 years of industry
experience after graduation and/or postdoc.
- Skilled in the art and practice of modern synthetic and
physical organic chemistry with demonstrated experience designing
and executing multistep synthesis of complex organic
- Competence with the use of modern spectroscopic methods applied
to structure determination, including NMR and HPLC-MS. Experience
in maintaining related instruments is highly preferred.
- Knowledge of safe laboratory practices, including the proper
procedures for handling chemicals and samples. Follow all safety
rules and regulations.
- Experience in computerized data management systems or
willingness to obtain proficiency.
- Store, organize, and maintain compound and reagent inventory.
Experience in sample management, inventory, and tracking is a
- Excellent oral and written communication skills.
- Experience in biorthogonal conjugation chemistry is highly
preferred but not necessary.
Keywords: Kodiak Sciences, Palo Alto , Scientist, Organic Chemistry, Other , Palo Alto, California
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